A
| Autor: | Ying-Yu, Zhang, Zhen-Yan, Fu, Jian, Wei, Wei, Qi, Gulinaer, Baituola, Jie, Luo, Ya-Jie, Meng, Shu-Yuan, Guo, Huiyong, Yin, Shi-You, Jiang, Yun-Feng, Li, Hong-Hua, Miao, Yong, Liu, Yan, Wang, Bo-Liang, Li, Yi-Tong, Ma, Bao-Liang, Song |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Mice
Knockout China Myosin Heavy Chains Myosin Type V Genetic Variation Membrane Proteins Membrane Transport Proteins Cholesterol LDL Hep G2 Cells Kazakhstan Pedigree Cytoskeletal Proteins Mice Protein Transport Asian People Intestinal Absorption Animals Humans Intestinal Mucosa Frameshift Mutation Protein Binding |
| Zdroj: | Science (New York, N.Y.). 360(6393) |
| ISSN: | 1095-9203 |
| Popis: | A high concentration of low-density lipoprotein cholesterol (LDL-C) is a major risk factor for cardiovascular disease. Although LDL-C levels vary among humans and are heritable, the genetic factors affecting LDL-C are not fully characterized. We identified a rare frameshift variant in the |
| Databáze: | OpenAIRE |
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