Autor: |
Mohammed M, Alanazi, Hazem, Elkady, Nawaf A, Alsaif, Ahmad J, Obaidullah, Hamad M, Alkahtani, Manal M, Alanazi, Madhawi A, Alharbi, Ibrahim H, Eissa, Mohammed A, Dahab |
Rok vydání: |
2021 |
Zdroj: |
RSC advances. 11(48) |
ISSN: |
2046-2069 |
Popis: |
A new series of 3-methylquinoxaline-based derivatives having the same essential pharmacophoric features as VEGFR-2 inhibitors have been synthesized and evaluated for their antiproliferative activities against two human cancer cell lines, MCF-7 and HepG-2. Compounds 15b and 17b demonstrated a significant antiproliferative effect with IC |
Databáze: |
OpenAIRE |
Externí odkaz: |
|