| Autor: |
Angelica de Lima das, Chagas, Leiny Paula de, Oliveira, Mauricio Vicente, Cruz, Renato Miranda de, Melo, Marina Pacheco, Miguel, Katia Flavia, Fernandes, Liliana Borges de, Menezes |
| Rok vydání: |
2021 |
| Zdroj: |
Materials (Basel, Switzerland). 15(4) |
| ISSN: |
1996-1944 |
| Popis: |
Polymeric membranes are a viable and sustainable option for the biotechnology industry from an economic and environmental point of view. In this study, we evaluated tissue response and tolerance to the implantation of a polymeric membrane prepared with cashew gum polysaccharide (CGP) associated with polyvinyl alcohol (PVA). The objective was to characterize the biocompatibility of the CGP/PVA membrane in vivo. Following the evaluation criteria of the ISO 10993-6 standard, we demonstrated that the CGP/PVA membrane showed moderate tissue reaction, with a non-irritating ISO pattern, a thinner fibrous capsule, and a smaller amount of collagen compared to the positive control group. At 30 and 60 days, the membrane presented a similar amount of mast cells to that observed in the negative control group. The data demonstrate that the CGP/PVA membrane presents biocompatibility in accordance with the ISO 10993-6 standard. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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