Autor: |
T A, Sheĭkina, G B, Belostotskaia, A F, Lepëkhin |
Rok vydání: |
1978 |
Předmět: |
|
Zdroj: |
Tsitologiia. 20(9) |
ISSN: |
0041-3771 |
Popis: |
HeLa G-63 cells irradiated by 5 krads of 6 degrees Co gamma-rays 1.5--2 hours after mitosis (G1-phase) were incubated in growth medium during 9 days. The number of proliferating and eliminated cells, the content of DNA per cell nucleus, and kinetics of the labeled cell fraction upon 3H-TdR continuous incubation were studied. It has been concluded that: during the giant cell growth the nuclear DNA is replicated periodically without following mitoses; 90% of cells are involved in such a cycle; the duration of the period of DNA synthesis in giant cells is the same as that in non-irradiated cells; the duration of the gap between two successive S-periods in giant cells is 2--6 times as long as the sum of G2+M+G1 periods in the normal non-irradiated cells. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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