[The effect of 5-hydroxyadamantan-2-one on morphological status of rats' brain tissues in local permanent ischemia conditions]

Autor: N R, Mirzoian, N G, Khostikian, V S, Meliksetian, K B, Alikhanian, A G, Stepanian, A A, Akopian, A M, Kukhtarova, N A, Bagdasarian
Rok vydání: 2013
Předmět:
Zdroj: Eksperimental'naia i klinicheskaia farmakologiia. 76(6)
ISSN: 0869-2092
Popis: The effect of 5-hydroxyadamantane-2-one was studied on morphological state of brain tissue of rats after the occlusion of left middle cerebral artery. It was shown that intraperitoneal administration of 5-hydroxyadamantane-2-on at dose 100mg/kg, in 30 minutes after occlusion and once daily for the following 6 and 12 days leads to significant regenerative processes in brain tissue. These processes were more profound after the 12-day treatment with 5-hydroxyadamanta-ne-2-one.
Databáze: OpenAIRE