[Reaferon treatment in acute HBsAG-positive viral hepatitis]

Autor: I P, Gorbarets, E S, Ketiladze, N A, Farber, N P, Bugaeva, D M, Braginskiĭ
Rok vydání: 1990
Předmět:
Zdroj: Klinicheskaia meditsina. 68(3)
ISSN: 0023-2149
Popis: Clinical, biochemical and serological examinations of 412 patients with acute HBsAg-positive virus hepatitis were conducted to assess therapeutic efficacy of Soviet recombinant alpha 2-interferon (reaferon). There were 309 cases of acute virus hepatitis B, 103 of delta infection (71--coinfection, 32--superinfection). The study and control groups were assigned randomly. Reaferon i.m. administration started on jaundice day 1-5 and lasted for 10-11 days. The treatment proved effective in acute hepatitis B running a moderately severe and severe course up to the development of acute hepatic encephalopathy. In delta infection reaferon produced response in coinfection only. In fulminant hepatitis the treatment was uneffective.
Databáze: OpenAIRE