| Popis: |
to study the concentration of vitamins in obese patients after bariatric surgery (BS).A total of 100 obese patients aged 19 to 61 years (78 women, 22 men). 20 patients (mean body mass index (BMI)--41.3 ± 8.2 kg/m²) had adjustable gastric banding (AGB), 40 patients--sleeve gastrectomy (SG) and 40--gastric bypass (GB) (mean BMI Group 41.1 ± 17.8 kg/m², and 45.9 ± 6.2 kg/m², respectively). The control group consisted of 10 healthy subjects (BMI--24.9 ± 3.2 kg/m²). We determined the serum level of vitamins B₁, B₂, B₅, B₆, B₉, B₁₂, C, D, niacin, biotin, and retinol-binding protein (RBP) before surgery and 1 year after it.There was a significant reduction ofvitamins C, B₆, B₅, D and RBP both before and after BS. More than half of patients after SG, also had initial reduction of niacin. A year after BS (AGB, SG, GB) the number of patients with deficiency of these vitamins remained the same or increased. Most patients with normal or even elevated levels ofvitamin B₂, niacin and folic acid, has been declining a year after BO. The concentration of the rest of the vitamins also significantly decreased a year after all operations, but their performance remained within normal limits.Levels of vitamins C, B₆ and D were reduced in more than 70% patients with obesity. The number of patients with low levels of vitamin C D, B₆, B₅, niacin, folic acid and RBP increased after BS. BS does not have a significant effect on the metabolism ofvitamins B₁, B₂, B₁₂ and biotin. |
