Variable suppression of feline bone marrow fibroblast colony-forming units by two isolates of feline leukemia virus

Autor: M L, Wellman, G J, Kociba, L E, Mathes
Rok vydání: 1991
Předmět:
Zdroj: American journal of veterinary research. 52(11)
ISSN: 0002-9645
Popis: Bone marrow fibroblast colony-forming units (CFU-F) were evaluated in cats experimentally infected with different, isolates of FeLV. Cats infected with the Kawakami-Theilen isolate of FeLV (FeLV-KT) had progressive decrease in the number of CFU-F at 2, 4, and 6 weeks after infection. The number of CFU-F in FeLV-KT-infected cats ranged from 38 to 70% of the preinoculation CFU-F value. Of 3 cats with FeLV-KT-induced suppression of CFU-F, 2 developed fatal nonregenerative anemia. Cats infected with the Rickard isolate of FeLV (FeLV-R) had more moderate decrease in the number of CFU-F at 2, 4, and 6 weeks after infection. The number of CFU-F in FeLV-R-infected cats ranged from 62 to 82% of the preinoculation CFU-F value. The FeLV-R-infected cats did not become anemic.
Databáze: OpenAIRE