| Autor: |
S, Rywik, L, Kłosiewicz-Latoszek, G, Broda, W B, Szostak |
| Rok vydání: |
1997 |
| Předmět: |
|
| Zdroj: |
Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego. 3(13) |
| ISSN: |
1426-9686 |
| Popis: |
62 patients with hyperlipidemia II and hypertension were 8 weeks on low fat and low cholesterol diet (acc. to EAS recommendations). If LDL-Chor = 4.1 mmol/l the diet was continued and 12 weeks treatment by fluvastatin (Lescol, Sandoz Pharma Ltd) started with control every 4 weeks Preliminary dosage 20 mg once daily in the evening increased to 40 mg if LDL-Ch3.5 mmol/l. After 12 weeks the mean level of T.Chol decreased by 21%, LDL-Ch by 29%, LDL-Ch/HDL-Ch by 31% and T.Chol/HDL-Ch by 24%. HDL-Ch increased by 8% and TG decreased by 5% but not significantly. The first goal of treatment (LDL-Ch4.14 mmol/l) achieved 73% and second (LDL-Chor = 3.5 mmol/l)-43.3% patients. In 2 patients treatment was discontinued (in one due to severe alimentary symptoms and in second-due to infection of respiratory tract with increase of SGOT and SGPT) and in next 2 the dosage was decreased to 20 mg/day (due to transitory alimentary symptoms). |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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