| Autor: |
J, Köpf, C, Hanson, U, Delle, A, Weimarck, U, Stierner |
| Rok vydání: |
1996 |
| Předmět: |
|
| Zdroj: |
Anticancer research. 16(2) |
| ISSN: |
0250-7005 |
| Popis: |
Four human melanoma cell lines with different copy numbers of chromosomes 9 and 21q, as studied by the G-band technique, fluorescent in situ hybridisation (FISH) and Polymerase chain reaction (PCR), were tested for their sensitivity to Interferon-alpha (IFN-alpha) and Interferon-beta (IFN-beta) in relation to dosage of interferon genes (#9) and interferon receptor genes (#21p). The two most sensitive cell lines were those containing the highest numbers of #9 per cell, while the number of #21q copies (receptor genes) seemed to have no influence on the interferon sensitivity. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
