| Autor: |
Diana G, Ferreira, Mariana, Temido-Ferreira, Hugo, Vicente Miranda, Vânia L, Batalha, Joana E, Coelho, Éva M, Szegö, Inês, Marques-Morgado, Sandra H, Vaz, Jeong Seop, Rhee, Matthias, Schmitz, Inga, Zerr, Luísa V, Lopes, Tiago F, Outeiro |
| Rok vydání: |
2016 |
| Předmět: |
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| Zdroj: |
Nature neuroscience. 20(11) |
| ISSN: |
1546-1726 |
| Popis: |
Synucleinopathies, such as Parkinson's disease and dementia with Lewy bodies, are neurodegenerative disorders that are characterized by the accumulation of α-synuclein (aSyn) in intracellular inclusions known as Lewy bodies. Prefibrillar soluble aSyn oligomers, rather than larger inclusions, are currently considered to be crucial species underlying synaptic dysfunction. We identified the cellular prion protein (PrP |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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Full text from SpringerLink