Significance of TIM-3 expression by CD4

Autor:	Sahar, Shariati, Atri, Ghods, Mahshid, Zohouri, Reza, Rasolmali, Abdol-Rasoul, Talei, Fereshteh, Mehdipour, Abbas, Ghaderi
Rok vydání:	2020
Předmět:	Adult CD4-Positive T-Lymphocytes Interleukin-2 Receptor alpha Subunit Breast Neoplasms Forkhead Transcription Factors CD8-Positive T-Lymphocytes Middle Aged Flow Cytometry T-Lymphocytes Regulatory Lymphatic Metastasis Humans Female Lymph Nodes Hepatitis A Virus Cellular Receptor 2 Aged
Zdroj:	Molecular immunology. 128
ISSN:	1872-9142
Popis:	T cell immunoglobulin and mucin domain-containing protein 3 (TIM-3), which is expressed by immune and nonimmune cells, has been shown to play immunoregulatory roles in the tumor microenvironment. In this study we assessed the expression of TIM-3 by T cells from tumor draining lymph nodes (TDLNs) of patients with breast cancer and its association with disease progression. Lymphocytes were isolated from 41 TDLNs, and flow cytometry was used to determine the expression of TIM-3 on CD4
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::5dfd3c4d622a0887e85fb5d035ec6d5d https://pubmed.ncbi.nlm.nih.gov/33068833 Zobrazit plný text záznamu Full Text from ScienceDirect