[Role of phospholipids in the realization of catecholamine action]

Autor: M N, Pertseva, Z P, Zheludkova
Rok vydání: 1978
Předmět:
Zdroj: Ukrainskii biokhimicheskii zhurnal (1. 50(6)
ISSN: 0201-8470
Popis: The involvement of phospholipids into the function of the hormonoreactive system realizing the catecholamine action on the skeletal muscle metabolism was studied at different stages of chicken ontogenetic development. The phospholipase "D" treatment of the chicken muscle homogenate removed the epinephrine activating effect on phosphorylase. Phosphatidylserine and phosphatidylinositol not only completely restore the epinephrine responsiveness of this system but also slightly intensify it. The cAMP and Ca2+ effects on muscle phosphorylase are also removed after the phospholipase "D" treatment. But they are not restored by phosphatidylserine and phosphatidylinositol. It is shown that these membrane phospholipids do not accelerate the origination of catecholamine reactivity of the above-mentioned hormonecompetent system in the process of embryonic development.
Databáze: OpenAIRE