Neurometabolic alterations in the nucleus accumbens of smokers assessed with

Autor:	Colette A, Steinegger, Niklaus, Zoelch, Andreas, Hock, Anke, Henning, Etna J E, Engeli, Erich, Seifritz, Lea M, Hulka, Marcus, Herdener
Rok vydání:	2021
Předmět:	Adult Male Magnetic Resonance Spectroscopy Smokers Glutamine Glycine Patient Acuity Glutamic Acid Tobacco Use Disorder Nucleus Accumbens Substance Withdrawal Syndrome Glutamates Tobacco Smoking Humans Inflammation Mediators Inositol
Zdroj:	Addiction biologyREFERENCES. 26(6)
ISSN:	1369-1600
Popis:	Tobacco use is one of the leading causes of premature death and morbidity worldwide. For smokers trying to quit, relapse rates are high, even after prolonged periods of abstinence. Recent findings in animal models highlight the role of alterations in glutamatergic projections from the prefrontal cortex onto the nucleus accumbens (NAc) in relapse vulnerability. Moreover, inflammatory responses in the NAc have been reported during withdrawal. A novel proton magnetic resonance spectroscopy (
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::5d8e3a512defea6a69d4aa00301e5fbc https://pubmed.ncbi.nlm.nih.gov/33825270 Zobrazit plný text záznamu Plný text