Fever temperatures impair hemolysis caused by strains of

Autor: Mihaela, Palela, Elena Diana, Giol, Andreia, Amzuta, Oxana G, Ologu, Razvan C, Stan
Rok vydání: 2021
Zdroj: Heliyon. 8(2)
ISSN: 2405-8440
Popis: Hemolysis modulates susceptibility to bacterial infections and predicts poor sepsis outcome. Hemolytic bacteria use hemolysins to induce erythrocyte lysis and obtain the heme that is essential for bacterial growth. Hemolysins are however potent immunogens and infections with hemolytic bacteria may cause a reversible fever response from the host that will aid in pathogen clearance. We hypothesized that fever temperatures impact the growth and infectivity of two hemolytic bacteria that are known to evoke fever in patients. To that end, we used high-sensitivity microcalorimetry to measure the evolution of heat production in fever-inducing strains of
Databáze: OpenAIRE