| Popis: |
OBJECTIVE: To compare the epidemiological and clinical features of lower respiratory tract infection(LRTI) caused by influenza virus A(ⅣA) and influenza virus B(ⅣB) in children. METHODS: The clinical data of 366 children with LRTI caused by influenza virus(Ⅳ), who were hospitalized in Yuying Children's Hospital of Wenzhou Medical University between 2010 and 2014, were analyzed retrospectively, and there were 272 cases caused by ⅣA and 94 cases caused by ⅣB. RESULTS: Ⅳ was mainly prevalent from December to March of the next year, with the predominance of ⅣA.There were small peaks of ⅣA prevalence in July or September every other year, and ⅣB was prevalent from December to March of the next year every other year.The children with LRTI caused by ⅣA alone had a significantly higher white blood cell(WBC) count and significantly higher percentages of children with increased WBC, abnormal serum sodium, and abnormal serum potassium than those caused by ⅣB alone(P < 0.05).However, there were no significant differences in age, sex, underlying diseases, clinical manifestations, and co-infection rate with bacteria or atypical pathogens between the two groups(P > 0.05).The rate of co-infection with respiratory syncytial virus(RSV) was significantly higher in the ⅣB group than in the ⅣA group(P < 0.01). CONCLUSIONS: ⅣA is prevalent in winter and spring every year and has small peaks in summer every other year, while ⅣB is prevalent in winter and spring every other year.Compared with ⅣB, ⅣA causes more cases of increased WBC and electrolyte disturbance.The children infected with ⅣB are more likely to be co-infected with RSV.The children with LRTI caused by ⅣA and ⅣB have similar clinical manifestations. |
