| Autor: |
G, Ciuffetti, L, Pasqualini, G, Fuscaldo, N, Piccioni, R, Paltriccia, E, Mannarino |
| Rok vydání: |
1995 |
| Předmět: |
|
| Zdroj: |
VASA. Zeitschrift fur Gefasskrankheiten. 24(2) |
| ISSN: |
0301-1526 |
| Popis: |
In order to see whether leucocyte-derived adhesion molecules are involved in ischaemia and reperfusion, the total and differential leucocyte counts and expression of the LFA complex i.e. CD11a/CD18 (LFA-1), CD11b/CD18 (Mac-1) and CD11c/CD18 (p 150,95) were monitored before and after standard cold and heat tests in 8 females with Raynaud's Disease and 8 matched controls. All patients suffered from vasoconstriction during the cold test which, compared with controls, was associated with fewer granulocytes expressing significantly more CD11b/CD18 (Mac-1) integrin and a significant degree of neutropenia persisting during reperfusion. Leucocyte-endothelial adhesive interactions may therefore occur during ischaemia and reperfusion. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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