| Autor: |
Pei-Hao, Chen, Kuo-Hua, Hung, Shih-Jung, Cheng, Kuang-Nan, Hsu |
| Rok vydání: |
2007 |
| Předmět: |
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| Zdroj: |
Acta neurologica Taiwanica. 15(4) |
| ISSN: |
1028-768X |
| Popis: |
Acute disseminated encephalomyelitis (ADEM) is a monophasic demyelinating disease of the central nervous system, typically occurring after infections or vaccinations. To our knowledge, scrub typhus has not been described in association with ADEM.A 77-year-old man was admitted with fever, convulsions and an altered level of consciousness. On neurological examination, the patient was stuporous and had nuchal rigidity and left hemiparesis. A generalized tonic-clonic seizure was observed. Serum and cerebrospinal fluid samples were positive for anti-Orientia tsutsugamushi antibody. Despite a 10-day course of parenteral minocycline, his clinical condition deteriorated. Serial cranial magnetic resonance images demonstrated progressively extensive areas of signal hyperintensity on conventional T2-weighted and fluid attenuated inversion recovery sequence images, mainly affecting the periventricular white matter. After administration of intravenous high-dose corticosteroids, the patient had limited improvement.This is the first identifiable case of ADEM temporally associated with scrub typhus alone. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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