| Autor: |
C, Lacroix, P, Poncet, G, Laine, C, Guyonnaud, M, Ray, S, Menager, O, Lafont |
| Jazyk: |
francouzština |
| Rok vydání: |
1987 |
| Předmět: |
|
| Zdroj: |
Journal of chromatography. 422 |
| Popis: |
The method reported here for determining pyrazinamide and its metabolites (2-pyrazinoic acid, 5-hydroxypyrazinamide, 5-hydroxypyrazinoic acid and pyrazinuric acid) consists of diluting urine or acid deproteinisation of serum followed by chromatography on a cation-exchange column. The column length and the detection system (ultraviolet or fluorimetry) allow for a very good separation of the different compounds; the sensitivity of the method makes it suitable for pharmacokinetic studies. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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