| Autor: |
B D, Korant, D C, Blomstrom, G J, Jonak, E, Knight |
| Rok vydání: |
1984 |
| Předmět: |
|
| Zdroj: |
The Journal of biological chemistry. 259(23) |
| ISSN: |
0021-9258 |
| Popis: |
Human interferons induce a protein of 15,000 daltons in human and bovine cells. This protein is located in the cytoplasm in a soluble form and is induced by concentrations of interferon which induce the antiviral state. Messenger RNA prepared from interferon-treated human and bovine cells contains a mRNA which yields on translation in vitro a protein similar in size to the 15-kDa protein induced by interferon in vivo. The human protein has been purified to homogeneity from interferon-treated human cells by ion-exchange chromatography and reverse-phase high-performance liquid chromatography. A comparison of the peptides generated by V8 protease from the human and bovine 15-kDa proteins reveals that the two proteins are similar but not identical. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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