[The induction of tolerance in mice for a human melanoma graft]

Autor:	T A, Bogush, A, Lokshin, G B, Smirnova, S F, Iushkov, I A, Karpov, G Sh, Ovumian, V N, Kastrykina, K L, Chimishkian
Rok vydání:	1990
Předmět:	Mice Inbred BALB C Skin Neoplasms Transplantation Heterologous Skin Transplantation Embryo Mammalian Liver Transplantation Mice Inbred C57BL Mice Immune Tolerance Mice Inbred CBA Animals Humans Transplantation Homologous Melanoma Neoplasm Transplantation
Zdroj:	Eksperimental'naia onkologiia. 12(5)
ISSN:	0204-3564
Popis:	Mouse skin allografts and intramuscular BRO human melanoma xenografts were successfully established in phenotypically normal mice after inducing immunological tolerance in the recipients. Tolerance was achieved by inoculating allogenic embryonic liver cells after the whole-body irradiation. No immunological rejection was evident in BRO xenografts for 34 days after transplantation. During this period the BRO cells invaded neighboring tissues and formed distant micrometastases in the lungs.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::5bbc61e77764d0a13ea86a857041ba82 https://pubmed.ncbi.nlm.nih.gov/2226261 Zobrazit plný text záznamu