Comparative accessory cell function of Langerhans cells isolated from mouse skin

Autor:	D R, Katz, G H, Sunshine
Rok vydání:	1986
Předmět:	T-Lymphocytes Cell Membrane Antigen-Presenting Cells Receptors Fc Mice Microscopy Electron Phagocytosis Langerhans Cells Concanavalin A Animals Peritoneal Cavity Cell Division Spleen Research Article
Zdroj:	British journal of experimental pathology. 67(2)
ISSN:	0007-1021
Popis:	We have isolated Fc receptor bearing cells from murine epidermis and examined these cells using both structural and functional methods. From 60 to 70% of these cells are Ia positive, phagocytic and express Mac 1 and F4.80 markers. They do not have Birkbeck granules in their cytoplasm. In functional studies these cells are not active as inducer cells in allogeneic and mitogen responses. The results do not support direct homology between these Langerhans cells and the interdigitating dendritic cell. Thus within the epidermis these cells may be more closely related to a macrophage, possibly involved in antigen uptake.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::5b60777eb88838b416374f902c6e194f https://pubmed.ncbi.nlm.nih.gov/3486670 Zobrazit plný text záznamu