| Autor: |
T W, Schultz, F M, Applehans, G W, Riggin |
| Rok vydání: |
1987 |
| Předmět: |
|
| Zdroj: |
Ecotoxicology and environmental safety. 13(1) |
| ISSN: |
0147-6513 |
| Popis: |
Twenty 2- and 3-position derivatives of pyridine (C5H5N) were tested following a short-term static protocol. Biological activity was monitored as population growth of Tetrahymena pyriformis. These data were combined with previously reported data for twenty 4-position derivatives. Structure-activity relationships were examined using Kow as the physicochemical descriptor. These data form three linear models: one for the non-H-polar derivatives and two for the H-polar derivatives. The latter two models are parallel but have no obvious basis for a priori selectivity. HPLC analysis for toxicant persistence shows that only the smaller non-H-polar derivatives have any significant abiotic loss over the duration of the biological testing. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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