| Autor: |
Carlos J, Cobeñas, Laura L, Lombardi, Priscila, Pereyra, Emanuel, De Rose, María José, Gogorza, Ana Paula, Spizzirri, Javier D, Ruscasso, Soledad Luján, Ferradas, Ángela Del Carmen, Suárez, Oscar R, Amoreo, Javier H, Zalba, Paula, Risso |
| Rok vydání: |
2020 |
| Předmět: |
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| Zdroj: |
Pediatric nephrology (Berlin, Germany). 36(9) |
| ISSN: |
1432-198X |
| Popis: |
We aimed to determine the prevalence of hypoalbuminemia in STEC-HUS patients with hemorrhagic colitis (HC) and whether serum albumin level (SAL), leukocyte count, hematocrit and serum sodium level (SSL) are prognostic markers of HC, central nervous system disease (CNSd) and/or dialysis requirement and evaluate if hypoalbuminemia is associated with fecal protein losses.We prospectively evaluated STEC-HUS patients treated at our institution from 9/2011 to 2/2019, analyzing the presence of HC, CNSd and dialysis requirement and SAL, SSL, leukocytes, hematocrit and α1-antitrypsin clearance.We evaluated 98 patients, with mean age of 33.3 months. SAL ≤ 29.5 g/l,24,600 leukocytes/mmAlmost all patients with HC had hypoalbuminemia, which behaves as a risk factor for HC, CNSd and dialysis requirement. No significant association was observed between elevated α1-antitrypsin clearance and hypoalbuminemia nor between elevated α1-antitrypsin clearance and HC. These findings could be related to the small number of evaluated patients. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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