Migratory flyway and geographical distance are barriers to the gene flow of influenza virus among North American birds

Autor:	Tommy Tsan-Yuk, Lam, Hon S, Ip, Elodie, Ghedin, David E, Wentworth, Rebecca A, Halpin, Timothy B, Stockwell, David J, Spiro, Robert J, Dusek, James B, Bortner, Jenny, Hoskins, Bradley D, Bales, Dan R, Yparraguirre, Edward C, Holmes
Rok vydání:	2011
Předmět:	Gene Flow Geography animal diseases virus diseases Genome Viral Article Birds Phylogeography Social Isolation Influenza A virus Influenza in Birds North America Animals Animal Migration Phylogeny
Zdroj:	Ecology letters. 15(1)
ISSN:	1461-0248
Popis:	Despite the importance of migratory birds in the ecology and evolution of avian influenza virus (AIV), there is a lack of information on the patterns of AIV spread at the intra-continental scale. We applied a variety of statistical phylogeographic techniques to a plethora of viral genome sequence data to determine the strength, pattern, and determinants of gene flow in AIV sampled from wild birds in North America. These analyses revealed a clear isolation-by-distance of AIV among sampling localities. In addition, we show that phylogeographic models incorporating information on the avian flyway of sampling proved a better fit to the observed sequence data than those specifying homogeneous or random rates of gene flow among localities. In sum, these data strongly suggest that the intra-continental spread of AIV by migratory birds is subject to major ecological barriers, including spatial distance and avian flyway.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::5abccece579dab4c687d4b61fd036b79 https://pubmed.ncbi.nlm.nih.gov/22008513 Zobrazit plný text záznamu Plný text