Pheochromocytoma in an 8-year-old patient with Multiple Endocrine Neoplasia Type 2A: Implications for Screening

Autor:	Rowland, Kathryn J, Chernock, Rebecca D, Moley, Jeffrey F
Jazyk:	angličtina
Rok vydání:	2013
Předmět:	Mutation Proto-Oncogene Proteins c-ret Adrenal Gland Neoplasms Humans Female Multiple Endocrine Neoplasia Type 2a Pheochromocytoma Child Article Early Detection of Cancer
Popis:	Childhood pheochromocytoma in the setting of multiple endocrine neoplasia type 2 (MEN2) remains rare and has not been reported under the age of 12. We present an 8-year-old female with known MEN 2A, C634Y RET mutation, diagnosed with a 6 cm pheochromocytoma requiring laparoscopic adrenalectomy. Given this patient's age at diagnosis, screening guidelines should recommend annual screening beginning at age 8 for patients with MEN 2B or MEN 2A codons 630 or 634 RET mutations.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::5a93536e7849b1c7e5b10d33946a7d26 https://europepmc.org/articles/PMC3983847/ Zobrazit plný text záznamu