Hospital epidemiology and antimicrobial susceptibility of isolated methicillin-resistant
| Autor: | Palapun, Waitayangkoon, Achitpol, Thongkam, Tanawat, Benjamungkalarak, Muanpetch, Rachayon, Aphisit, Thongthaisin, Tanittha, Chatsuwan, Arsa, Thammahong, Direkrit, Chiewchengchol |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Male Methicillin-Resistant Staphylococcus aureus Staphylococcus aureus Microbial Sensitivity Tests biochemical phenomena metabolism and nutrition Staphylococcal Infections bacterial infections and mycoses Thailand Anti-Bacterial Agents Tertiary Care Centers Humans Female Child Retrospective Studies Research Article |
| Zdroj: | Pathog Glob Health |
| ISSN: | 2047-7732 |
| Popis: | Background: Increased rates of Staphylococcus aureus resistance and its morbidity and mortality have raised concern about the strategy of antibiotic use. Objectives: This study aimed to determine the prevalence of methicillin-resistant S. aureus (MRSA) and vancomycin-resistant S. aureus (VRSA) isolates among Thai patients with S. aureus infection and to identify risk factors and appropriate antibiotics for these resistant strains. Methods: Data of culture-proven S. aureus isolates from clinical specimens during 2017 in King Chulalongkorn Memorial Hospital, Thailand, were retrospectively collected and classified as methicillin-sensitive S. aureus or MRSA by cefoxitin screening and oxacillin minimum inhibitory concentration by the Vitek 2 system. Each isolate was also tested for susceptibility to teicoplanin, erythromycin, clindamycin, linezolid, trimethoprim/sulfamethoxazole, ciprofloxacin, moxifloxacin, tetracycline, doxycycline, and vancomycin by Vitek 2. Demographic information and comorbidities from medical records were reviewed to identify risk factors for S. aureus infection. Results: MRSA isolates were identified in 147 (17%) of 890 patients with no different ratio in adults or children. A higher proportion of MRSA in hospital-acquired settings was observed (27% vs. 12%; p |
| Databáze: | OpenAIRE |
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