| Autor: |
Natalie J, Norman, Si Tong, Bao, Lynne, Curts, Tiffani, Hui, Shao-Liang, Zheng, Tiffany, Shou, Ana, Zeghibe, Izzy, Burdick, Hannah, Fuehrer, Adrian, Huang |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
The Journal of organic chemistry. 87(15) |
| ISSN: |
1520-6904 |
| Popis: |
Inspired by crystal structures, we designed and achieved a catalyst-free Michael reaction for the preparation of an N1-alkyl pyrazole in a high yield (90%) with excellent regioselectivity (N1/N299.9:1). The scope of this protocol has been extended to accomplish the first general regioselective N1-alkylation of 1 |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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