| Autor: |
Aashray, Singareddy, Ashley S E, Lee, Patrick L, Sweeney, Abigael E, Finkle, Howard L, Williams, Paula M, Buchanan, Noah H, Hillman, Joyce M, Koenig |
| Rok vydání: |
2020 |
| Předmět: |
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| Zdroj: |
Journal of perinatology : official journal of the California Perinatal Association. 41(6) |
| ISSN: |
1476-5543 |
| Popis: |
Histologic chorioamnionitis (HCA) is a placental inflammation linked to preterm birth and adverse neonatal outcome. The neutrophil-lymphocyte ratio (NLR) can identify various inflammatory disorders, however its utility in HCA is not clear. Our goal was to examine NLR values and HCA diagnoses in at-risk pregnancies and neonates.We retrospectively analyzed the EHR of mothers and preterm (33 wk GA) neonates with or without HCA (identified by placental histology). The NLR was calculated from complete blood counts in laboring women and in their neonates (0-24 h of life).In 712 consecutive gestations, 50.8% had HCA (26.5% fetal HCA). The neonatal NLR (0-12 h, 13-24 h) predicted fetal HCA better than chance alone (p = 0.01 and 0.002, respectively).Early NLR elevation in preterm neonates is consistent with a diagnosis of fetal HCA. The NLR may identify preterm neonates at risk for HCA-related complications. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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