Cerebral atrophy in a vitamin B12-deficient infant of a vegetarian mother
| Autor: | Celebi, Kocaoglu, Fatih, Akin, Hüseyin, Caksen, Saltuk Buğra, Böke, Sükrü, Arslan, Serhat, Aygün |
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| Rok vydání: | 2014 |
| Předmět: |
Cerebral Cortex
Male Turkey Case Study Vitamin B12 Diet Vegetarian Developmental regression Infant Mothers Vitamin B 12 Deficiency Cerebral atrophy Failure to thrive Magnetic Resonance Imaging Macrocytic anaemia Vitamin B 12 Breast Feeding Treatment Outcome hemic and lymphatic diseases Vitamin B Complex Humans Anemia Macrocytic Atrophy |
| Zdroj: | Journal of Health, Population, and Nutrition |
| ISSN: | 1606-0997 |
| Popis: | In developed countries, vitamin B12 (cobalamin) deficiency usually occurs in children, exclusively breastfed ones whose mothers are vegetarian, causing low body stores of vitamin B12. The haematologic manifestation of vitamin B12 deficiency is pernicious anaemia. It is a megaloblastic anaemia with high mean corpuscular volume and typical morphological features, such as hyperlobulation of the nuclei of the granulocytes. In advanced cases, neutropaenia and thrombocytopaenia can occur, simulating aplastic anaemia or leukaemia. In addition to haematological symptoms, infants may experience weakness, fatigue, failure to thrive, and irritability. Other common findings include pallor, glossitis, vomiting, diarrhoea, and icterus. Neurological symptoms may affect the central nervous system and, in severe cases, rarely cause brain atrophy. Here, we report an interesting case, a 12-month old infant, who was admitted with neurological symptoms and diagnosed with vitamin B12 deficiency. |
| Databáze: | OpenAIRE |
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