| Autor: |
Thakur, Sunitha B., Durando, Manuela, Milans, Soledad, Cho, Gene Y., Gennaro, Lucas, Sutton, Elizabeth J., Giri, Dilip, Morris, Elizabeth A. |
| Jazyk: |
angličtina |
| Rok vydání: |
2017 |
| Předmět: |
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| Popis: |
To measure the apparent diffusion coefficient (ADC) values in estrogen receptor-positive (ER+) and axillary lymph node-negative (LN-) invasive breast cancer and investigate the correlation of ADC with Oncotype Dx test recurrence scores (ODxRS).This was a Health Insurance Portability and Accountability Act (HIPAA)-compliant single-site retrospective study. Patients underwent preoperative 3.0T MRI scans with additional diffusion-weighted imaging sequential scans (b = 0, 600 and b = 0, 1000 s/mmInvasive breast cancers, when scored as low-risk by ODxRS, had significantly higher ADC values compared with intermediate/high-risk lesions for both ADCPreliminary findings suggest that lesion ADC values correlate with recurrence risk likelihood stratified using ODxRS. Hence, ADC is a potential surrogate biomarker for tumor aggressiveness.3 Technical Efficacy: Stage 5 J. Magn. Reson. Imaging 2018;47:401-409. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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