| Autor: |
E, Sartori, S, Belliard, C, Chevrier, P, Trebon, J, Chaperon, G, Edan |
| Jazyk: |
francouzština |
| Rok vydání: |
2006 |
| Předmět: |
|
| Zdroj: |
Revue neurologique. 162(5) |
| ISSN: |
0035-3787 |
| Popis: |
Cognitive deficit in multiple sclerosis (MS) is a frequent early feature in the disease course, which conditions patients' overall disability. The goals of this study were to validate a reproducible brief screening battery written in French and to examine cognitive risk profiles in patients with a mild physical disability.Cognitive performances of 40 patients with EDSS4.5 were compared with those of a control group. The study was completed with an analysis of socio-demographic, clinical and psychological variables (questionnaires).Three tests were discriminative with satisfactory predictive values (positive: 88 percent; negative: 96 percent) and a time duration30 minutes: PASAT (hard condition), backward digit span, learning stage of California Verbal Learning Test. Four variables were associated with cognitive deficit: educational level11 years, age40 years, pathological laughing-crying, unemployment.Our brief battery is an easy and reproducible tool. Completed with warning signs indicating the need for neuropsychological screening, this tool provides the practitioner with a global means of assessing disease activity and potentially therapeutic efficacy. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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