[The impact of patient and tumor related prognostic factors on survival in non-medullary differentiated thyroid cancer. A study of 125 cases]
| Autor: | R, Dănilă, Ramona, Popovici, Al, Grigorovici, Lidia, Ionescu, D, Timofte, L, Lefter, L V, Boiculesei, Maria Cristina, Ungureanu, Cr, Dragomir |
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| Jazyk: | Romanian; Moldavian; Moldovan |
| Rok vydání: | 2008 |
| Předmět: |
Male
Age Factors Carcinoma Papillary Follicular Kaplan-Meier Estimate Middle Aged Prognosis Survival Analysis Treatment Outcome Predictive Value of Tests Risk Factors Lymphatic Metastasis Thyroidectomy Humans Female Thyroid Neoplasms Neoplasm Staging Proportional Hazards Models Retrospective Studies |
| Zdroj: | Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi. 111(4) |
| ISSN: | 0048-7848 |
| Popis: | The aim of the study was to assess the impact of patient--(age) and tumor--related factors (size, extrathyroidal invasion, distant metastasis, multicentricity and lymphatic metastasis) on survival of patients with differentiated thyroid cancer (DTC).A clinical retrospective study was carried out on a series of 125 patients operated for non medullary DTC in the IIIrd Surgical Unit, in the period 1990-2005. The disease specific survival (DS) was calculated using the Kaplan Meyer method and Cox regression univariate and multivariate analysis was used to assess the impact of prognostic factors on DS.The actual DS at 5, 10, and 15 yrs was 81.3%. Clinicopathological factors significant on univariate and multivariate regression were age over 45 yrs (p = .01), tumor size4 cm (p = .00), macroscopical extrathyroidal invasion (p = .000) and distant metastasis (p = .000). |
| Databáze: | OpenAIRE |
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