| Autor: |
Rafel, Simó-Vicens, Jeppe E, Kirchhoff, Bernardo, Dolce, Lea, Abildgaard, Tobias, Speerschneider, Ulrik S, Sørensen, Morten, Grunnet, Jonas G, Diness, Bo H, Bentzen |
| Rok vydání: |
2017 |
| Předmět: |
|
| Zdroj: |
British journal of pharmacology. 174(23) |
| ISSN: |
1476-5381 |
| Popis: |
Small conductance calcium-activated potassium (KUsing site-directed mutagenesis, binding determinants for AP14145 inhibition were explored. AP14145 selectivity and mechanism of action were investigated by patch-clamp recordings of heterologously expressed KAP14145 was found to be an equipotent negative allosteric modulator of KAP14145 is a negative allosteric modulator of K |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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