Seropositivity to hepatitis C virus in Tunisian haemodialysis patients

Autor: S, Jemni, K, Ikbel, M, Kortas, J, Mahjoub, L, Ghachem, J M, Bidet, K, Boukef
Rok vydání: 1994
Předmět:
Zdroj: Nouvelle revue francaise d'hematologie. 36(5)
Popis: The prevalence of anti-hepatitis C virus (anti-HCV) antibodies and of hepatitis B markers (HBs antigen, anti-hepatitis B core antigen) was assessed in 63 haemodialysis patients from the Tunisian Sahel. As measured by second generation ELISA assays (Ortho and Organon), the frequency of anti-HCV antibodies was 42% (27/63), while 4 patients (6.3%) were HBs Ag positive and 30 (47.6%) anti-HBc positive. Anti-HCV seropositivity was significantly correlated with duration of dialysis (p = 0.007) and number of blood transfusions (10 units, p = 0.0004). Among 12 subjects with a history of abnormal ALAT levels, 10 were anti-HCV positive (p = 0.0016) and the results suggest hepatitis C viral infection to be the main cause of liver disease in haemodialysis patients in Tunisia.
Databáze: OpenAIRE