| Autor: |
D, Timofte, Roxana, Livadariu, V, Bintintan, C, Diaconu, Lidia, Ionescu, A A, Sandberg, D C, Mariciuc, R, Dănilă |
| Rok vydání: |
2014 |
| Předmět: |
|
| Zdroj: |
Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi. 118(2) |
| ISSN: |
0048-7848 |
| Popis: |
Adenocarcinoma of the pancreas presents a major threat with a 5-years survival rate of 5%. Whipple pancreaticoduodenectomy (PD) is the standard procedure for cephalo-pancreatic neoplasm. After an extended resection and reconstruction of superior gastrointestinal tract the digestive physiology might be heavily disrupted. A literature review of metabolic alterations of patients who suffered a major pancreatic resection is performed, regarding micronutrients, lipid absorption and pancreatogenic diabetes. Long-term survivors following PD generally have a satisfactory nutritional status although with subclinical iron, vitamin D and selenium deficiency. These patients should be followed-up also regarding these micronutrients and properly dietary supplemented when necessary, also considering the increased life expectancy. Approximately 17-25% of patients will develop insulin-dependent diabetes but pancreatogenic diabetics have elevated levels of serum insulin and minimal or absent response to food intake, as opposed to a type I diabetics, where insulin serum is normal or elevated and there is an exaggerated response to ingestion of sugar. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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