| Autor: |
Katherine Ann, Scott, Sini, Shah, Angus George, Dalgleish, Wai Man, Liu |
| Rok vydání: |
2013 |
| Předmět: |
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| Zdroj: |
Anticancer research. 33(10) |
| ISSN: |
1791-7530 |
| Popis: |
Cannabinoids are the bioactive components of the Cannabis plant that display a diverse range of therapeutic qualities. We explored the activity of six cannabinoids, used both alone and in combination in leukaemic cells. Cannabinoids were cytostatic and caused a simultaneous arrest at all phases of the cell cycle. Re-culturing pre-treated cells in drug-free medium resulted in dramatic reductions in cell viability. Furthermore, combining cannabinoids was not antagonistic. We suggest that the activities of some cannabinoids are influenced by treatment schedules; therefore, it is important to carefully select the most appropriate strategy in order to maximise their efficacy. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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