Application of disposable plastic microfluidic device arrays with customized chemistries to multiplexed biochemical assays

Autor: A J, Ricco, T D, Boone, Z H, Fan, I, Gibbons, T, Matray, S, Singh, H, Tan, T, Tian, S J, Williams
Rok vydání: 2002
Předmět:
Zdroj: Biochemical Society transactions. 30(2)
ISSN: 0300-5127
Popis: Plastic microfluidic array platforms and synergistic multiplexed assay chemistries are under development for a variety of applications, including assays of gene expression, proteomics, genotyping, DNA sequencing and fragment analysis, sample preparation and high-throughput pharmaceutical discovery. The low production costs of plastic substrates makes possible economical single-use device arrays, eliminating cleaning and sample-to-sample carryover contamination. Hundreds of microchannels and reservoirs are readily included on a single microtitre-plate-size substrate, enabling the manufacture of highly parallel fluidic array systems to increase throughput and speed.
Databáze: OpenAIRE