| Autor: |
Douglas J, Fort, Michael B, Mathis, Faith, Kee, Paul, Whatling, David, Clerkin, Jane, Staveley, Clifford, Habig |
| Rok vydání: |
2016 |
| Předmět: |
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| Zdroj: |
Environmental toxicology and chemistry. 37(2) |
| ISSN: |
1552-8618 |
| Popis: |
Development of an acute oral toxicity test with a terrestrial-phase amphibian was considered necessary to remove the uncertainty within the field of agrochemical risk assessments. The bullfrog (Lithobates catesbeianus) was selected for use as it is a representative of the family Ranidae and historically this species has been used as an amphibian test model species. Prior to definitive study, oral gavage methods were developed with fenthion and tetraethyl pyrophosphate. Dimethoate and malathion were subsequently tested with both male and female juvenile bullfrogs in comprehensive acute oral median lethal dose (LD50) studies. Juvenile bullfrogs were administered a single dose of the test article via oral gavage of a single gelatin capsule of dimethoate technical (dimethoate) or neat liquid Fyfanon |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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