A decreasing trend in
| Autor: | Sorin, Motoi, Dan Bogdan, Navolan, Daniel, Malita, Ioana, Ciohat, Dragos, Nemescu, Carmen, Manciuc, Florin, Gorun, Tatjana, Vilibic-Cavlek, Daniel, Boda, Marius, Craina, Amadeus, Dobrescu |
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| Rok vydání: | 2020 |
| Předmět: | |
| Zdroj: | Experimental and Therapeutic Medicine |
| ISSN: | 1792-0981 2008-2010 |
| Popis: | Toxoplasmosis is a zoonotic infection caused by the obligate intracellular apicomplexan parasite Toxoplasma gondii (T. gondii). T. gondii infection is a cause of congenital infection worldwide. Primary infection or the reactivation of latent infection during pregnancy may lead to fetal infection and to congenital toxoplasmosis syndrome. Seropositive pregnant women are generally protected from maternal-fetal transmission of T. gondii, although exceptions exist. The aim of our study was to analyze the dynamics of T. gondii seroprevalence during a 10-year period and to correlate it with age and demographic features of pregnant women. We tested 6,889 pregnant women in Timisoara, Romania, for IgG-anti-T. gondii antibodies, in two successive periods: i) 2008-2010 (group 1: 1,457 participants); and ii) 2015-2018 (group 2: 5,432 participants). For each participant, data on age and area of residence were collected. Our results showed that in the Western Region of Romania T. gondii seroprevalence in pregnant women declined from 43.79 to 38.81% in the last ten years. This trend was observed in both urban (40.53 vs. 34.85%) and rural areas (52.22 vs. 46.22%). A higher seroprevalence rate was found in rural than in urban areas. In addition, we found an increasing tendency of seroprevalence related to the age of pregnant women. |
| Databáze: | OpenAIRE |
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