| Autor: |
F, Dore, S, Bonfigli, S, Pardini, M, Longinotti |
| Rok vydání: |
1995 |
| Předmět: |
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| Zdroj: |
Haematologica. 80(5) |
| ISSN: |
0390-6078 |
| Popis: |
In this study we determined serum IL-8 levels in 18 untransfused patients with beta-thalassemia intermedia and in 14 subjects affected by HbH disease. As reported in polytransfused homozygous beta-thalassemia, untransfused beta-thalassemia and HbH disease show significantly (p0.005) higher serum IL-8 levels than normal controls. Our data suggests that there could be an intrinsic cause for the IL-8 increase in thalassemia intermedia. We think than the hyperactivity of thalassemic macrophages related to chronic hemolysis is the main cause for the increment in cytokines, such as IL-8, found in thalassemic syndromes. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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