Synthesis of 2-chloropurine ribosides with chiral amino acid amides at C6 and their evaluation as A

Autor: Maria Ya, Berzina, Barbara Z, Eletskaya, Alexei L, Kayushin, Elena V, Dorofeeva, Olga I, Lutonina, Ilya V, Fateev, Alexander S, Paramonov, Maria A, Kostromina, Evgeniy A, Zayats, Yulia A, Abramchik, Dmitriy V, Maltsev, Ludmila V, Naumenko, Alena S, Taran, Dmitry S, Yakovlev, Alexander A, Spasov, Anatoly I, Miroshnikov, Roman S, Esipov, Irina D, Konstantinova
Rok vydání: 2022
Předmět:
Zdroj: Bioorganic chemistry. 126
ISSN: 1090-2120
Popis: A series of purine ribonucleosides bearing chiral amino acid amides at the C6 position of 2-chloropurine was synthesized. Molecular docking of the synthesized analogs of 2-chloroadenosine by their affinity for A
Databáze: OpenAIRE