| Autor: |
Z, Skrzydlewski, J, Niklinski, S, Kiluk, M, Kiluk, B, Musiatowicz, E, Zaremba, E, Skrzydlewska, A, Klepacki |
| Rok vydání: |
1997 |
| Předmět: |
|
| Zdroj: |
Minerva chirurgica. 52(3) |
| ISSN: |
0026-4733 |
| Popis: |
The usefulness of post operative serum CA 15-3 determination was evaluated in a group of 57 breast cancer patients. CA 15-3 was assayed at baseline and every 3 months for a median follow-up of 34 months. Recurrence-free survival probability for patients with elevated serum CA 15-3 levels before surgery was 53.5% versus 88% for patients with normal serum CA 15-3 levels (p0.201). In 12 of the 15 patients with increased trend for CA 15-3 during follow-up, elevated CA 15-3 levels preceded (10 patients) coincided (2 patients) with the clinical detection of tumour recurrence, providing a predictive value of an increased trend of 80%. In the group of 10 patients who showed elevated serum CA 15-3 levels prior to the detection of recurrence, the median load-time was 5 months/(range 3-11 months). We concluded that CA 15-3 had prognostic value in breast cancer. Serial determinations of CA 15-3 was consistent with the treatment results. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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