[A Case of Locally Advanced Gastric Cancer after Neoadjuvant Chemotherapy]

Autor: Tatsuya, Okamoto, Keita, Tanaka, Kimihiro, Yonemitsu, Taro, Munechika, Masako, Nomi, Hiroshi, Maeno, Shuji, Nagao, Shunji, Kawamoto, Takakazu, Sasaguri, Katsuo, Sueishi
Rok vydání: 2016
Předmět:
Zdroj: Gan to kagaku ryoho. Cancerchemotherapy. 42(12)
ISSN: 0385-0684
Popis: A 60s male was admitted to our hospital because of appetite loss and nausea. After examination, he was diagnosed with type 3 advanced gastric cancer in the antrum. Abdominal computed tomography showed gastric cancer invasion to the left liver lobe. We initiated neoadjuvant chemotherapy using S-1 plus CDDP after laparoscopic gastrojejunostomy. S-1 was orally administered for 3 weeks followed by a 2-week drug-free period. CDDP was administered intravenously on day 8 of each course. After 5 courses of chemotherapy, the gastric cancer was reduced in size. We therefore performed total gastrectomy with D2-affiliated left liver resection. S-1 plus CDDP is expected to improve outcomes in unresectable or locally advanced gastric cancer.
Databáze: OpenAIRE