| Popis: |
Including own results a survey is given of the side effects of beta-receptor blockers on the plasma lipoprotein metabolism. The formation of a from the coronary-preventive point of view unfavourable lipoprotein risk profile under influence of individual beta-receptor blockers, among others propranolol, seems to be connected with an inhibition of a key enzyme in the lipoprotein metabolism, the lecithin-cholesterol-acyl transferase. Talinolol does not show these side effects. It is recommended to control the triglyceride level and the HDL cholesterol before the induction and after the beginning of a therapy with beta-receptor blockers and to use talinolol instead of propranolol in pre-existing dyslipoproteinaemia or in unfavourable changes during the treatment. |
