| Autor: |
S V, Prylutska, O V, Lynchak, V V, Kostjukov, M P, Evstigneev, O V, Remeniak, V K, Rybalchenko, Yu I, Prylutskyy, U, Ritter, P, Scharff |
| Rok vydání: |
2019 |
| Předmět: |
|
| Zdroj: |
Experimental oncology. 41(2) |
| ISSN: |
1812-9269 |
| Popis: |
Cisplatin (Cis-Pt) is a widely used anticancer drug but its therapeutic efficiency is limited by hemato-, cardio-, hepato-, nephro- and neurotoxicity. Complexation of Cis-Pt with CTo estimate the antitumor effects of С60-Cis-Pt nanocomplex in Lewis lung carcinoma (LLC) and analyze hematological toxicity in tumor-bearing mice.Complexation of CComputer simulation demonstrated the formation of С60-Cis-Pt nanocomplex in physiological medium and its stability due to the hydrophobic interactions. Treatment with CTreatment with C |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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