[The effect of ionizing radiation with low dose rate on the state of electron transfer chain of enterocyte mitochondria of rat small intestine]

Autor:	L V, Grubskaia, V M, Voĭtsitskiĭ, S V, Khizhniak
Rok vydání:	2012
Předmět:	Male Uncoupling Agents Dose-Response Relationship Radiation Oxidative Phosphorylation Mitochondria Rats Electron Transport Kinetics Adenosine Triphosphate Enterocytes Oxygen Consumption Radiation Ionizing Intestine Small Animals 2 4-Dinitrophenol Oxidation-Reduction
Zdroj:	Ukrains'kyi biokhimichnyi zhurnal (1999 ). 84(1)
Popis:	The influence of ionizing radiation with low absorbed dose rate (55 mGy x min(-1)) in 1, 12 and 24 hours after irradiation in doses of 0.1; 0.5 and 1.0 Gy on functional state of the electron transfer chain of the rat small intestine mitochondria was investigated by assessment of the oxygen consumption rate. The uncoupling of oxidation and phosphorylation, a decrease of phosphorylation rate and inhibition of ATP hydrolysis reactions were established in mitochondria in dependence on the irradiation dose and time interval after irradiation. The functional peculiarities of the oxidation-phosphorylation coupling sites of the mitochondrial electron transfer chain were detected.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::542b2bc7bea4fd767afe5e44462a55a3 https://pubmed.ncbi.nlm.nih.gov/22679757 Zobrazit plný text záznamu