[The effect of cyclosporin A and oligomycin on the nonspecific permeability of the mitochondria inner membrane]

Autor: S A, Novgorodov, T I, Gudz', D B, Zorov, Iu E, Kushnareva, Iu B, Kudriashov
Rok vydání: 1991
Předmět:
Zdroj: Biokhimiia (Moscow, Russia). 56(3)
ISSN: 0320-9725
Popis: The effect of oligomycin and cyclosporine A on Ca(2+)-induced nonspecific permeability of the inner mitochondrial membrane was under study. Both oligomycin and cyclosporine A were able to prevent the activation of nonspecific permeability; however, but cyclosporine A was the only agent which could restore the initial permeability of the inner mitochondrial membrane. The effect of cyclosporine A was not shown to be mediated through redistribution of Ca2+ ions between different subpopulations of mitochondria.
Databáze: OpenAIRE