Acute renal failure due to idiopathic tubulo-intestinal nephritis and uveitis: 'TINU syndrome'. Case report and review of the literature

Autor: A, Sessa, M, Meroni, G, Battini, G, Viganò, P L, Brambilla, C T, Paties
Rok vydání: 2000
Předmět:
Zdroj: Journal of nephrology. 13(5)
ISSN: 1121-8428
Popis: Acute renal failure due to idiopathic tubulo-interstitial nephritis associated with bilateral uveitis (TINU syndrome) is a rare clinical event, contracted mainly by girls or women. Here we report the clinical follow-up regarding a 22-year-old woman with acute renal failure (creat. clearance 13.5 ml/min) due to idiopathic tubulo-interstitial nephritis documented by renal biopsy, after bilateral uveitis which healed with local prednisone. The clinical history and the clinical follow-up of our patient were typical of the TINU syndrome. We were able to exclude all diseases causing acute tubulo-interstitial nephritis such as systemic infection, hypersensitivity to drugs, Behcet's disease, Sjogren syndrome, sarcoidosis, systemic lupus or vasculitides. The patient recovered after systemic prednisone.
Databáze: OpenAIRE