Evidence of intrinsic differences in the light scattering properties of tumorigenic and nontumorigenic cells

Autor:	J R, Mourant, A H, Hielscher, A A, Eick, T M, Johnson, J P, Freyer
Rok vydání:	1999
Předmět:	Mice Light Neoplasms Tumor Cells Cultured Animals Mice Nude Scattering Radiation Cell Count Cell Size Rats
Zdroj:	Cancer. 84(6)
ISSN:	0008-543X
Popis:	The objective of this study was to determine whether there are intrinsic differences in the light scattering properties of tumorigenic and nontumorigenic cells from a multistep carcinogenesis model.Wavelength-dependent and polarization-dependent light scattering properties of cell suspensions were measured.Statistically significant differences were found between the tumorigenic and nontumorigenic cells. CONCLUSIONS. Differences in the light scattering properties of tumorigenic and nontumorigenic cells are attributed to a change in the average size of the scattering centers on the order of a few ten of nanometers. This work is relevant to the development of noninvasive optical methods for cancer diagnosis.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::52c2c552041dd0fb9f2ca0c51b5890bf https://pubmed.ncbi.nlm.nih.gov/9915139 Zobrazit plný text záznamu Plný text